Southbound lanes of the Hume Highway have reopened after a crash near Jugiong on Saturday afternoon.
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A northbound lane closed after a second crash about 45 minutes after the first has also reopened.
Fire crews and paramedics responded to the initial crash near Berremangra Road just after 1pm.
Both southbound lanes were closed for the SnowyHydro South Care helicopter to land.
Traffic was redirected through Burley Griffin Way and the Olympic Highway while emergency services worked at the scene, with delays of about an hour reported.
The crews then turned their attention to the second crash, a single-vehicle rollover, and closed a northbound lane just after 2pm.
It is not yet known whether there were any injuries from the two crashes.
