Haulin' the Hume, a historic truck rally, will journey 300 kilometres along the Old Hume Highway from Camden to Yass, via Goulburn.

The convoy will pass through Picton, Yerrinbool, Mittagong and Berrima before stopping in Goulburn for lunch.

The trucks will then continue through to Breadalbane and Gunning (around 3pm) before they finish the procession at Yass. 

Founder Bruce Gunter came up with the idea for a procession along the Old Hume Highway after his father became ill.

"I had my dad's restored truck and he had always wanted to take it for a run along the highway," Mr Gunter said.

More than 140 trucks turned up for the first convoy in 2011. After the success of the first rally, Mr Gunter took the opportunity to raise money for charity.

The rally will raise funds for Aspect, a service provider for people on the autistic spectrum.

Mr Gunter holds the charity close to his heart as his son has autism. "We wanted to give something back," he said. "We put a lot of the money back into country areas."

Over the past four runs, Haulin' the Hume has raised more than $100,000.

A disability swing was installed in Coronation Park, Yass in 2017 and a disability swing will be installed in Goulburn this year.

He puts the success of the event down to the efforts of the community, the council, the police and the RMS to make the day happen.

"The run has become very popular," Mr Gunter said. "It's quite visually spectacular. The rally is probably the largest road run in the Southern Hemisphere."

The Haulin' the Hume historical truck rally will be held on Saturday March 30. The trucks will enter Yass from the north, along Yass Valley Way, around 4pm. Spectators usually line the sides of the road to catch the display. Mr Gunter said people should pitch their seats at 3.30pm so as not to miss the action.

An auction and dinner will be held at Yass Soldiers' Memorial Hall on the Saturday evening to raise funds for Aspect. Drivers will stay at the Yass Showground and town's motels before heading to the old 'Gasoline Alley' on Laidlaw Street on Sunday morning, for a final farewell and awards ceremony outside of the Yass Valley Men's Shed.

Mr Gunter will also pay homage to the truck drivers involved in the Razorback mountain blockades on March 29. The blockade involved a number of truck-drivers who blocked the highway between Camden and Picton for nine days in protest in 1979.